Blar i NTNU Open på forfatter "Castañeda-Zegarra, Sergio"
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Synthetic lethality between DNA repair factors Xlf and Paxx is rescued by inactivation of Trp53
Castañeda-Zegarra, Sergio; Xing, Mengtan; Gago-Fuentes, Raquel; Sæterstad, Siri; Oksenych, Valentyn (Journal article; Peer reviewed, 2019)Non-homologous end joining (NHEJ) is a DNA repair pathway that senses, processes and ligates DNA double-strand breaks (DSBs) throughout the cell cycle. During NHEJ, core Ku70 and Ku80 subunits bind DSBs as a heterodimer ...